Dihydrogen Monoxide Research Division - dihydrogen monoxide info - satirical (and funny) site illustrating how ignorance, unfounded fears and wobbly risk assessment can be whipped up into a crisis (about water). Buy a Ban Dihydrogen Monoxide T-shirt, DHMO HazMat Vial, or the DHMO Educator's Kit at the online store.
The Comic Book Periodic Table of the Elements - a well-done collection of occurrences of element names in comic books. Click on an element and see comic book pages where that element is mentioned or used. Collected by professors(!) in the Chemistry Department at University of Kentucky.
Grocery Store Wars | Join the Organic Rebellion - I'm really conflicted on this one since it's so funny, but I certainly don't want to promote the myth that organic food is somehow superior to conventionally raised crops. This links to a organic food promotion site that has a 5-minute Star Wars parody featuring Cuke Skywalker and storm trooper eggs with good effects and sound.
Delphion Gallery of Obscure Patents - nominated by users of Delphion's intellectual property site, some of these will leave you scratching your head.
The Elements, by Tom Lehrer - Just about everyone knows about mathematician/satiricist Tom Lehrer's wonderful song, The Elements. Well Mike Stanfill is a graphic artist who uses the song as a showcase for his design services (Requires Flash).
Science Jokes - a large (>2500) collection of science humor collected and categorized by Joachim Verhagen divided up by discipline with many subsections. Contains PG-13 and R-rated material.
Top Ten Comical Compounds - these jokes are sight gags—funny if you have some knowledge of chemical structure and nomenclature
Molecules with Silly or Unusual Names - list of unusual chemical names due to the systematic or trivial names involved
Wacky Patent of the Month - a page on the business site of a Florida patent attorney. Has archives to view past winners(?).
Peep Research - A thorough examination of what Peeps are made of. Chemistry, physics, physical chemistry, surgery and behavioral sciences all weigh in on the make-up of these ubiquitous marshmallow chicks.
OXymoron Humour Archive - good collection at a U.K. site
Chemistry Page of Profession Jokes - a few chemistry jokes & links to engineers’ jokes
Jupiter Scientific's Chemistry Jokes - a couple dozen from a small publisher
Math, Science and Engineering Jokes - set of science jokes
chemistry.org Joke-a-Rama - these jokes on an ACS site aren’t all funnier than others but at least they’ve been peer-reviewed